Thermo Fisher Scientific RANK Polyclonal Antibody
RANK (CD265) 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific RANK Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 466–616 of human TNFRSF11A (NP_003830.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805208 |
Product Specific Information
- Immunogen sequence:
RGPLPQCAYG MGLPPEEEAS RTEARDQPED GADGRLPSSA RAGAGSGSSP GGQSPASGNV TGNSNSTFIS SGQVMNFKGD IIVVYVSQTS QEGAAAAAEP MGRPVQEETL ARRDSFAGNG PRFPDPCGGP EGLREPEKAS RPVQEQGGAK A - Positive Samples: HT-29, Mouse brain, Rat kidney
- Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full-length mouse RANK cDNA encodes a type I transmembrane protein with extracellular and cytoplasmic domains. The extracellular domain contains two potential N-linked glycosylation sites and shares significant amino acid homology with other members of the TNFR family. Human and murine RANK share 81% amino acid identity in their extracellular domains.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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