Thermo Fisher Scientific HOXC11 Monoclonal Antibody (OTI4B8), TrueMAB
HOXC11 단백질을 인식하는 Mouse monoclonal 항체로, Western blot, IHC, ICC, Flow cytometry에 사용 가능. Human 시료에 반응하며, Lyophilized 형태로 제공. 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B8 |
| Immunogen | Full length human recombinant protein of human HOXC11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The HOXC11 gene belongs to the homeobox family, encoding transcription factors that regulate morphogenesis in multicellular organisms.
Mammals have four homeobox gene clusters (HOXA, HOXB, HOXC, HOXD), each located on different chromosomes.
HOXC11 is part of the HOXC cluster on chromosome 12 and binds to the promoter of lactase-phlorizin hydrolase, potentially involved in early intestinal development.
An alternatively spliced variant encoding a shorter isoform has been described, though its full-length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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