Thermo Fisher Scientific SH3PXD2A Monoclonal Antibody (OTI1H9), TrueMAB
SH3PXD2A 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Human, Mouse, Rat에 반응합니다. WB에서 1:2,000 희석으로 사용되며, 동결건조 형태로 제공됩니다. 세포 침습 및 ECM 분해 관련 연구에 적합합니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 299–395 of human SH3PXD2A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation, and invasiveness of certain cancer cells.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs), and phosphoinositides.
Acts as an organizer protein enabling NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and localization.
In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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