Thermo Fisher Scientific ACADM Monoclonal Antibody (OTI10A5), TrueMAB
ACADM 단백질을 인식하는 Mouse 모노클론 항체로 Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat 시료에 반응. 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 미토콘드리아 지방산 산화 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A5 |
| Immunogen | Full length human recombinant protein of human ACADM produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The ACADM gene encodes the medium-chain specific (C4–C12 straight chain) acyl-Coenzyme A dehydrogenase.
This homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid β-oxidation pathway.
Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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