
Thermo Fisher Scientific pro Eosinophil peroxidase Polyclonal Antibody
Human pro Eosinophil peroxidase를 인식하는 Rabbit polyclonal antibody. Western blot 및 IHC에 사용 가능. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C 유지 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 50–100 of human pro Eosinophil peroxidase (pro EPO) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C. Avoid freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: proEPO.
Target Information
EPX mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils.
It shows inhibitory activity toward Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
Allelic variants in EPX are associated with Japanese cedar pollinosis, a type I allergic disease causing seasonal rhinitis and conjunctival symptoms.
Defects in EPX cause eosinophil peroxidase deficiency (EPD), an autosomal recessive defect with nuclear hypersegmentation, hypogranulation, and negative peroxidase staining.
Subcellular Location: Cytoplasmic granule.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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