Thermo Fisher Scientific SLC1A2 Polyclonal Antibody
SLC1A2 단백질을 인식하는 sheep polyclonal antibody로, WB 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성 보유. EAAT2 특이성 확인. 연구용으로 장기 보관 시 -20°C에서 안정적으로 유지 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 500–550 of rat SLC1A2 conjugated to an immunogenic carrier protein was used as the antigen. Target family: GLT-1; UniProt ID: P31596-1; NCBI Node ID: 10114; Antigen range: 500–550; Antigen length: 573. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen shares 95% identity with human and mouse sequence.
- Specificity: EAAT2.
Target Information
Excitatory amino acid transporter 2 (EAAT2) is a membrane-bound solute transporter protein responsible for clearing the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Proper glutamate clearance prevents neuronal damage from excessive activation of glutamate receptors. Mutations or decreased expression of EAAT2 are associated with amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants of this gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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