Thermo Fisher Scientific ADAMTS13 Recombinant Rabbit Monoclonal Antibody (7B2Z8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7B2Z8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ADAMTS13 (Q76LX8). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ADAMTS13,uniProtId:Q76LX8-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:1427,antigenImageFileName:MA5-42805_ADAMTS13_Q76LX8-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42805_ADAMTS13_Q76LX8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911946

Product Specific Information

Positive test controls include: Mouse liver, Mouse spleen, Mouse plasma, Rat plasma.

Immunogen sequence: LSPGAPLKGR PPSPGFQRQR QRQRRAAGGI LHLELLVAVG PDVFQAHQED TERYVLTNLN IGAELLRDPS LGAQFRVHLV KMVILTEPEG APNITANLTS S

Target Information

ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.