Thermo Fisher Scientific NKG2A Polyclonal Antibody
인간 NKG2A(KLRC1) 단백질을 인식하는 Rabbit Polyclonal 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능합니다. Affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KLRC1 (Accession P26715), corresponding to amino acid residues M1–Y40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851807 |
Product Specific Information
This antibody detects endogenous levels of total KLRC1.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without prior activation. They also regulate specific humoral and cell-mediated immunity.
The protein encoded by this gene belongs to the killer cell lectin-like receptor (NKG2) family, a group of transmembrane proteins preferentially expressed in NK cells. These proteins are characterized by a type II membrane orientation and a C-type lectin domain.
NKG2A forms a complex with KLRD1/CD94 and is involved in recognition of MHC class I HLA-E molecules in NK cells. The NKG2 gene family is clustered on chromosome 12, and four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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