Thermo Fisher Scientific PLA2G2A Polyclonal Antibody
PLA2G2A 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC 등 다양한 응용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용 전용 제품.
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Thermo Fisher Scientific PLA2G2A Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PLA2G2A (Accession P14555), corresponding to amino acid residues I29–C79 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851808 |
Product Specific Information
Antibody detects endogenous levels of total PLA2G2A.
Target Information
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements.
This gene product belongs to group II, which contains secreted forms of PLA2 — extracellular enzymes with low molecular mass that require calcium ions for catalysis.
It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids. This process is thought to participate in the regulation of phospholipid metabolism in biomembranes.
Several alternatively spliced transcript variants with different 5′ UTRs have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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