Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Chimeric Recombinant Mouse Monoclonal Antibody (Sb#14)
SARS-CoV-2 스파이크 단백질 RBD를 인식하는 키메릭 리콤비넌트 마우스 단클론 항체로, ELISA 및 기능적 억제 실험에 적합합니다. HEK293 세포에서 발현되었으며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1 µg/mL |
| Functional Assay | Assay-dependent |
| Inhibition Assay | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1, Fc |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Sb#14 |
| Immunogen | This clone was originally isolated in the form of a synthetic nanobody (sybody) via a target swap selection procedure against RBD-vYFP using ribosomal display and against RBD-Fc fusion during phage display rounds. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody recognizes and binds the SARS-CoV-2 C-terminal receptor binding domain (RBD) located in the extracellular portion of the spike protein.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The Spike (S) protein is essential for viral attachment, fusion, and entry, making it a critical target for antibody, inhibitor, and vaccine development.
The receptor-binding domain (RBD, S-RBD) of the Spike protein binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors, exhibiting higher affinity than the SARS-CoV RBD.
S1 contains the RBD that specifically interacts with ACE2 on target cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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