Thermo Fisher Scientific MRCK gamma Polyclonal Antibody
Human MRCK gamma 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20~1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 세포 골격 재구성 연구용으로 적합.
- 카탈로그번호
- PA563988
- 판매단위
- pk
카탈로그
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRCK gamma. Recombinant protein control fragment (Product #RP-103424) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644100 |
Product Specific Information
Immunogen sequence:
SNDIFQVGEC RRVQQLTLSP SAGLLVVLCG RGPSVRLFAL AELENIEVAG AKIPESRGCQ VLAAGSILQA RTPVLCV
Ortholog sequence identity:
- Mouse: 83%
- Rat: 87%
Target Information
CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene.
It acts as a downstream effector of CDC42 in cytoskeletal reorganization and contributes to actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation.
Belongs to the AGC protein kinase family, DMPK subfamily.
Contains:
- N-terminal kinase domain
- Coiled-coil domain
- Kinase inhibitory motif (KIM)
- Variable region
- Cysteine-rich domain
- Pleckstrin homology (PH) domain
- Citron homology (CNH) domain
- C-terminal CDC42/RAC interactive binding (CRIB) domain
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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