Thermo Fisher Scientific RIC8 Polyclonal Antibody
Western blot과 IHC(파라핀) 실험에 적합한 RIC8 단클론 항체. 사람, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Resistance RIC8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: HeLa, Jurkat
Target Information
Guanine nucleotide exchange factor (GEF) that can activate some, but not all, G-alpha proteins. It activates GNAI1, GNAO1, and GNAQ, but not GNAS, by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic chromosome movement by stimulating G(i)-alpha protein, possibly leading to release of G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing G(q)-coupled receptor-mediated ERK activation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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