Thermo Fisher Scientific UCP1 Polyclonal Antibody
UCP1 단백질을 검출하기 위한 Rabbit Polyclonal 항체로, Western blot 및 면역조직화학(IHC)에 최적화되어 있습니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol 버퍼에 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human UCP1 (Accession P25874), corresponding to amino acid residues A127–T177 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900736 |
Product Specific Information
This antibody detects endogenous levels of total UCP1.
Target Information
Mitochondrial uncoupling proteins (UCPs) are members of the mitochondrial anion carrier protein family. They decouple oxidative phosphorylation from ATP synthesis, dissipating energy as heat (mitochondrial proton leak). UCPs facilitate anion transfer across the mitochondrial membrane and proton return, thereby reducing mitochondrial membrane potential. Expression of UCP1 is specific to brown adipose tissue, which functions in thermogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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