Thermo Fisher Scientific LOXL2 Monoclonal Antibody (OTI8G5), TrueMAB
인간 LOXL2 단백질을 인식하는 단클론 항체로, IHC(P)에서 1:150 희석으로 사용 가능. 동결건조 형태로 제공되며, PBS 버퍼(8% 트레할로오스 포함)에 용해 가능. 결합 실험용으로 재탈염 권장. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 152–450 of human LOXL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the lysyl oxidase gene family. The prototypic member is essential for the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin.
A highly conserved amino acid sequence at the C-terminus is sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is less conserved and may contribute to roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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