Thermo Fisher Scientific Phospho-Histone H2B (Ser15) Polyclonal Antibody
Phospho-Histone H2B (Ser15)에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간, 마우스, 랫트 반응성을 보입니다. 액상 형태로 -20°C에서 보관하며 연구용으로 사용됩니다.
- 카탈로그번호
- PA5105775
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HIST1H2BB (Accession P33778), corresponding to amino acid residues around phosphorylated Ser15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817174 |
Product Specific Information
Antibody detects endogenous levels of Histone H2B only when phosphorylated at Ser15.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). These structures compact DNA into chromatin, regulating accessibility for transcription, repair, replication, and maintaining chromosomal stability. H2B also exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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