Thermo Fisher Scientific TRPA1 Polyclonal Antibody
TRPA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. 인간 조직에 반응하며 IHC(P)에서 5–10 µg/mL 희석으로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.1% sodium azide를 포함한 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA533089
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific TRPA1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) [IHC(P)]
Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from internal region of human TRPA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550548 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gibbon, Monkey (100%)
- Marmoset (94%)
- Dog, Bovine, Elephant (89%)
- Rat, Bat, Panda, Horse, Rabbit (83%)
For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction.
It is a transformation-associated gene product in lung epithelia, with protein distribution primarily restricted to sensory neurons.
Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage.
TRPA1 protein is also widely expressed outside of the CNS and is dysregulated during oncogenic transformation.
Its structure is highly related to ankyrin and transmembrane proteins, and it may play a role in signal transduction and growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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