Thermo Fisher Scientific TRHR Polyclonal Antibody
TRH 수용체를 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. Dog, Horse, Human 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 PBS 버퍼에 0.1% sodium azide를 포함하고 있습니다.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Horse, Human, Sheep, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human TRH Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550547 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Sheep, Dog, Elephant, Panda, Horse, Pig (100%);
Marmoset, Mouse, Rat, Bovine, Hamster, Opossum, Turkey, Chicken, Lizard, Xenopus (94%);
Stickleback (88%); Rabbit, Zebrafish (81%). - For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer.
- After incubation with the primary antibody, slides were treated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to the G-protein coupled receptor 1 family.
It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon TRH binding.
TRH-R functions as a neurotransmitter and neuro regulator, controlling receptor dimerization and hormone-induced receptor trafficking.
It is widely expressed in the thyrotroph cells of the anterior pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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