Thermo Fisher Scientific Exendin 4 Monoclonal Antibody (20)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1:32,000

-

Product Specifications

Species Reactivity

Chemical

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

20

Immunogen

synthetic exendin-4

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.03 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1074297

Product Specific Information

ABS 012-20-02 detects exendin-4 from human samples. This antibody does not cross react with GLP-1, GLP-2 or glucagon.

ABS 012-20-02 has been successfully used in ELISA procedures. ABS 012-20-02 binds to exendin-4 when coated on ELISA wells and reacts specifically with exendin-4 in solution giving a Ka of 1.6x10E8 in an inhibition ELISA. The binding between ABS 012-20-02 and exendin-4 is disrupted by 4.5 M MgCl2.

There is full reaction with exendin-4 (9-39) when ABS 012-20-02 is used as coat in ELISA showing an epitope in the 9 - 39 region.

Target Information

Exendin-4 is a 39-amino-acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon-secretin family of peptide hormones and neuropeptides. Exendin-4 is a potent agonist of the GLP-1 receptor and hence a potent stimulator of insulin secretion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.