Thermo Fisher Scientific Phospho-PDGFRB (Tyr751) Monoclonal Antibody (G.13.6)
Phospho-PDGFRB (Tyr751) 단일클론 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. 액상 형태로 -20°C 보관하며, 연구용으로만 사용됩니다.
- 카탈로그번호
- MA514823
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G.13.6 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr751 of human PDGF receptor β |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10986575 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PDGFRB is a receptor tyrosine kinase implicated in atherogenesis and cell transformation by the SIS oncogene. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the receptor is a homodimer or heterodimer composed of both PDGFR alpha and beta polypeptides. The PDGFRB gene is located on chromosome 5, flanked by genes for GM-CSF and M-CSF receptor, potentially involved in the 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB (CD140b) with ETV6 can result in chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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