
Thermo Fisher Scientific CENPA Monoclonal Antibody (H.577.2)
CENPA 단백질을 인식하는 Rabbit monoclonal 항체(H.577.2)로, Western blot, ICC/IF, IP에 사용 가능. 마우스 시료에 반응하며, 비특이적 히스톤 단백질과 교차 반응 없음. 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | H.577.2 |
| Immunogen | Synthetic peptide corresponding to the amino terminus of mouse CENP-A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 23.4 µg/mL |
| Purification | Affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_10980200 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other histone proteins, including Histone H3.
Target Information
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes.
CENPA encodes a centromere protein which contains a histone H3-related histone fold domain required for targeting to the centromere.
CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces one or both copies of conventional histone H3 in the (H3-H4)₂ tetrameric core of the nucleosome particle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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