Thermo Fisher Scientific PSIP1 Monoclonal Antibody (E.493.5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50

-

Immunocytochemistry (ICC/IF)

1:250-1:400

-

Flow Cytometry (Flow)

1:100

-

ChIP assay (ChIP)

10 µL/10^6 cells

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

E.493.5

Immunogen

Synthetic peptide corresponding to amino acids surrounding Lys461 of human LEDGF if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PSIP1,uniProtId:O75475-1,ncbiNodeId:9606,antigenRange:461,antigenLength:530,antigenImageFileName:MA5-14821_PSIP1_O75475-1_Rabbit.svg,antigenImageFileNamePDP:MA5-14821_PSIP1_O75475-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

9 µg/mL

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_11009140

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.