Thermo Fisher Scientific NTAL Monoclonal Antibody (NAP-07), PE
NTAL 단백질을 인식하는 마우스 단클론 항체로 PE 형광물질이 결합되어 있음. 인간 및 마우스 시료에 반응하며 Flow Cytometry에 적합. 세포막 지질 뗏목 구성요소 연구에 유용. 연구용으로만 사용 가능.
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Applications
- Flow Cytometry (Flow): Tested dilution 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NAP-07 |
| Immunogen | Recombinant cytoplasmic domain (aa 91–243) of human NTAL |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745561 |
Additional Formats
Product Specific Information
This antibody reacts with an intracellular epitope of Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25–30 kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B lymphocytes, NK cells, and myeloid cells.
Target Information
NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells, and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and also acts as a negative regulator in mast cells. In mast cells, NTAL contributes to some activation processes, partially overlapping with LAT function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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