Thermo Fisher Scientific ATG9A Monoclonal Antibody (14F2 8B1), Alexa Fluor 488

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

5 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Armenian hamster / IgG

Class

Monoclonal

Type

Antibody

Clone

14F2 8B1

Immunogen

peptide sequence HPEPVPEEGSEDELPPQVHK of human ATG9A C-terminus if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ATG9A,uniProtId:Q7Z3C6-1,ncbiNodeId:9606,antigenRange:819-839,antigenLength:839,antigenImageFileName:MA1-149-A488_ATG9A_Q7Z3C6-1_Armenian_hamster.svg,antigenImageFileNamePDP:MA1-149-A488_ATG9A_Q7Z3C6-1_Armenian_hamster_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Alexa Fluor™ 488 Alexa Fluor™ 488 Alexa Fluor™ 488

View additional formats

• Unconjugated
• Request custom conjugation

Excitation/Emission Max

499/520 nm View spectra

Form

Liquid

Concentration

1.0 mg/mL

Purification

Protein A

Storage buffer

PBS with 1.0mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Dry ice (international)

RRID

AB_2723938

Product Specific Information

MA1-149A-488 was produced in Armenian hamster and detects ATG9 in human, rat and mouse samples. In Immunofluorescence applications, MA1-149A488 shows accumulation and redistribution of ATG9 in response to starvation-induced autophagosome assembly.

Target Information

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.