Thermo Fisher Scientific SPINK7 Polyclonal Antibody
인간 SPINK7 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA551287
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of human SPINK7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636734 |
Product Specific Information
This antibody detects endogenous levels of total SPINK7 protein.
Target Information
SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein containing one Kazal-like domain and is thought to function as a serine protease inhibitor.
The SPINK7 gene is located on human chromosome 5, which comprises approximately 181 million base pairs and encodes around 1,000 genes. Chromosome 5 is associated with several genetic conditions, including:
- Cockayne syndrome (via ERCC8 gene)
- Familial adenomatous polyposis (via APC tumor suppressor gene)
- Treacher Collins syndrome (caused by insertions/deletions in TCOF1)
- Cri du chat syndrome (deletion of the p arm of chromosome 5)
- Therapy-related acute myelogenous leukemia and myelodysplastic syndrome (deletion of 5q or entire chromosome 5)
Probable serine protease inhibitor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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