Thermo Fisher Scientific COL15A1 Polyclonal Antibody
COL15A1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:10~1:50 희석으로 사용 가능. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS(40% glycerol) 저장, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of human COL15A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636735 |
Product Specific Information
This antibody detects endogenous levels of total COL15A1 protein.
Target Information
The COL15A1 gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen is widely distributed in tissues, with the strongest expression in basement membrane zones, suggesting a role in adhering basement membranes to underlying connective tissue stroma.
The C-terminal fragment of type XV collagen, known as restin, is a potentially antiangiogenic protein related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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