Thermo Fisher Scientific CPEB1 Polyclonal Antibody
CPEB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC-P, ICC/IF, IP에 사용 가능. 고순도 항원 친화 크로마토그래피 정제, 1 mg/mL 농도, -20°C 보관. 인간, 마우스, 랫트 반응성.
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- PA11100
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:500 | – |
| Immunocytochemistry (ICC/IF) | 1:50–1:500 | View 1 publication |
| Immunoprecipitation (IP) | – | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C H(545) S M E G L R H H S P L M R N Q K N(562) of human CPEB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2083772 |
Product Specific Information
PA1-1100 detects recombinant mouse and rat CPEB (cytoplasmic polyadenylation element binding protein).
It has been successfully used in Western blot, ICC/IF, and IHC-P procedures.
By Western blot, this antibody detects approximately 62 kDa protein representing recombinant mouse CPEB.
The immunogen is a synthetic peptide corresponding to residues C H(545) S M E G L R H H S P L M R N Q K N(562) of human CPEB, which is completely conserved in mouse.
The immunizing peptide (Cat. # PEP-171) is available for use in neutralization and control experiments.
Target Information
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis.
Leukotrienes are arachidonic acid metabolites implicated in various inflammatory responses such as asthma, arthritis, and psoriasis.
This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit its activation.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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