Thermo Fisher Scientific GREM1 Polyclonal Antibody
GREM1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 검증 완료. Human 시료에 반응하며, Protein G 정제 및 1 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2.5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues Q(52)PGSRNRGRGQGRGTA(67) of human CKTSF1B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2113288 |
Product Specific Information
- Suggested positive control: human colon cancer tissue.
Target Information
In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on chromosome 15q13→q15.
DRM-specific mRNA is expressed in various human tissues, including brain, ovary, intestine, and colon.
Down-regulation of DRM has been associated with tumor progression, supporting the hypothesis that human DRM may play an important role in neuroembryological development and carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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