Thermo Fisher Scientific THRB Polyclonal Antibody
THRB 단백질을 인식하는 염소 유래 다클론 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며 액상 형태로 제공됩니다. 다양한 종(개, 마우스, 랫드)에 반응이 예측됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA518778
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific THRB Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (REELQKSIGHKP) corresponding to the internal amino acids of THRB (amino acids 201–213, UniProt ID: P10828-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980374 |
Product Specific Information
This antibody is predicted to react with canine, mouse, and rat based on sequence homology.
Target Information
Thyroid hormone receptors (TR), also known as c-erbA-2, are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to hormone response elements after activation by thyroid hormones. These receptors regulate metabolic processes, growth, and development by controlling expression of genes such as growth hormone, malic enzyme, and hepatic proteins.
There are two main forms of TR:
- TR alpha (chromosome 17)
- TR beta (chromosome 3)
Each has two isoforms: TR alpha-1/alpha-2 and TR beta-1/beta-2.
TRv alpha-2 does not bind T3 and acts as a strong negative regulator of functional TR.
The gene encoding thyroid hormone receptor beta-1 is NR1A2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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