Thermo Fisher Scientific NF2 Polyclonal Antibody
NF2 단백질(Merlin)을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. 인간 및 제브라피쉬 반응성, IHC(P) 등 다양한 응용 가능. 고순도 정제 및 안정적인 액상 형태로 제공되며 연구용으로 사용됩니다.
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Thermo Fisher Scientific NF2 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Zebrafish |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EKSKHLQDQLK) corresponding to the internal amino acids of NF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10975725 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that link cytoskeletal components with cell membrane proteins. Merlin interacts with cell-surface proteins, proteins involved in cytoskeletal dynamics, and those regulating ion transport.
This gene is expressed at high levels during embryonic development; in adults, significant expression occurs in Schwann cells, meningeal cells, lens, and nerve.
Mutations in NF2 are associated with neurofibromatosis type II, characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and several minor isoforms arise from alternatively spliced transcripts.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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