Thermo Fisher Scientific TYRO3 Monoclonal Antibody (OTI2D11), TrueMAB
TYRO3 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot, IHC, ICC, IP 등 다양한 응용에 적합. Human 시료 반응성, IgG1 아이소타입, 동결건조 형태로 제공. 세포 신호전달 및 생리적 과정 연구에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D11 |
| Immunogen | Full length human recombinant protein of human TYRO3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces extracellular matrix signals into the cytoplasm by binding ligands such as TULP1 or GAS6. It regulates processes including cell survival, migration, and differentiation. Ligand binding induces dimerization and autophosphorylation, creating docking sites for downstream signaling molecules. TYRO3 activation is involved in neuron protection, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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