Thermo Fisher Scientific TYRO3 Monoclonal Antibody (OTI9B12), TrueMAB
TYRO3 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC, Flow, IP 등 다양한 응용에 적합. 인간 시료 반응성. 동결건조 형태이며 PBS/trehalose 버퍼에 보존. 연구용으로 신호전달 및 세포 생리 연구에 활용 가능.
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Thermo Fisher Scientific TYRO3 Monoclonal Antibody (OTI9B12), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9B12 |
| Immunogen | Full-length human recombinant TYRO3 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm. It binds ligands such as TULP1 or GAS6 and regulates cell survival, migration, and differentiation.
Ligand binding induces dimerization and autophosphorylation of TYRO3, creating docking sites for downstream signaling molecules.
Activated TYRO3 participates in neuron protection, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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