Thermo Fisher Scientific BCOR Polyclonal Antibody
인간 BCOR 단백질에 특이적인 Rabbit Polyclonal Antibody로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA584927
- 판매단위
- pk
카탈로그
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BCOR. Recombinant protein control fragment (Product #RP-107488) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792076 |
Product Specific Information
Immunogen sequence:
LRVDRKRKVS GDSSHTETTA EEVPEDPLLK AKRRRVSKDD WPEREMTNSS SNHLEDPHYS ELTNLKVCIE LTGLHPKKQR HLLHLRERWE QQVSAADGKP G
Target Information
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 Lys-4 (H3K4me3) and Lys-36 (H3K36me2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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