
Thermo Fisher Scientific Phospho-Chemokine Receptor 6 (Thr360, Ser361) Polyclonal Antibody
인산화된 CCR6(Thr360/Ser361)을 인식하는 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CCR6 around the phosphorylation site of Thr360/Ser361 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
CCR6 is a member of the beta chemokine receptor family, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. It is preferentially expressed by immature dendritic cells and memory T cells. The ligand for this receptor is macrophage inflammatory protein 3 alpha (MIP-3α). CCR6 plays a key role in B-lineage maturation and antigen-driven B-cell differentiation, and may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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