
Thermo Fisher Scientific Phospho-Chemokine Receptor 6 (Ser357) Polyclonal Antibody
인간 CCR6 단백질의 Ser357 인산화 부위를 인식하는 토끼 폴리클로날 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CCR6 around the phosphorylation site of Ser357 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
CCR6 is a member of the beta chemokine receptor family, predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. Its ligand, macrophage inflammatory protein 3 alpha (MIP-3α), plays a key role in B-lineage maturation and antigen-driven B-cell differentiation. CCR6 may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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