Thermo Fisher Scientific CCL5 Monoclonal Antibody (OTI10G5), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CCL5 (RANTES) is a chemokine gene located on chromosome 17q.
It encodes a secreted protein involved in immune regulation and inflammation.
CCL5 acts as a chemoattractant for monocytes, memory T helper cells, and eosinophils, induces histamine release, and activates eosinophils.
It is one of the major HIV-suppressive factors produced by CD8+ cells and serves as a natural ligand for CCR5, suppressing replication of R5 strains of HIV-1.
Alternative splicing produces multiple isoforms.
Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.