Thermo Fisher Scientific CCL5 Monoclonal Antibody (OTI10G5), TrueMAB
인간 CCL5 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며 PBS 버퍼에 8% 트레할로스를 포함합니다. 연구용으로만 사용 가능하며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10G5 |
| Immunogen | Full length human recombinant protein of human CCL5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CCL5 (RANTES) is a chemokine gene located on chromosome 17q.
It encodes a secreted protein involved in immune regulation and inflammation.
CCL5 acts as a chemoattractant for monocytes, memory T helper cells, and eosinophils, induces histamine release, and activates eosinophils.
It is one of the major HIV-suppressive factors produced by CD8+ cells and serves as a natural ligand for CCR5, suppressing replication of R5 strains of HIV-1.
Alternative splicing produces multiple isoforms.
Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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