Thermo Fisher Scientific GluR2 Recombinant Rabbit Monoclonal Antibody (JU20-43)
GluR2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC(P), ICC/IF에 사용 가능. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션. 뇌 시냅스 가소성 연구 및 글루탐산 수용체 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU20-43 |
| Immunogen | Synthetic peptide within Human GluR2 (aa 181–230) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810071 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Glutamate-activated ion channels are divided into two classes:
- NMDA receptors (NMDAR): Sensitive to N-methyl-D-aspartate
- AMPA receptors (AMPAR): Activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid
AMPARs consist of four Glutamate Receptor Subunits (GluR1–4) and are essential for excitatory neurotransmission in the brain. The GluR2 subunit is particularly important in synaptic plasticity processes such as long-term depression (LTD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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