Thermo Fisher Scientific PPARA Monoclonal Antibody (OTI2F3), TrueMAB
인간 PPARA 단백질(aa 145-420)에 특이적인 Mouse Monoclonal Antibody (OTI2F3). Western blot 및 Immunocytochemistry에 사용 가능. Affinity chromatography로 정제된 1 mg/mL 액상 항체로, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 145–420 of human PPARA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Peroxisome proliferators are non-genotoxic carcinogens that exert their effects through interaction with members of the nuclear hormone receptor family, termed peroxisome proliferator-activated receptors (PPARs). These ligand-dependent intracellular proteins stimulate transcription of specific genes by binding to DNA sequences after activation by appropriate ligands. PPARs are activated by compounds such as clofibric acid, nafenopin, WY-14,643, and certain fatty acids. They can induce transcription of acyl coenzyme A oxidase and cytochrome P450 (CYP450) A6 through specific response elements. PPAR, like other nuclear hormone receptors, forms heterodimers with retinoid X receptor (RXR) alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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