Thermo Fisher Scientific PPARA Monoclonal Antibody (OTI2E7), TrueMAB
PPARA 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, ICC/IF, Flow cytometry에 적합합니다. Human 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. 안정적인 PBS/BSA/glycerol buffer로 장기 보관이 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 145–420 of human PPARA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.68 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Peroxisome proliferators are non-genotoxic carcinogens that exert their effect through the nuclear hormone receptor family known as peroxisome proliferator-activated receptors (PPARs). These ligand-dependent intracellular proteins regulate transcription of specific genes by binding to DNA sequences upon activation by appropriate ligands. PPARs are activated by compounds such as clofibric acid, nafenopin, WY-14,643, and certain fatty acids. They can induce transcription of acyl coenzyme A oxidase and cytochrome P450 (CYP450) A6 via interaction with specific response elements. PPARs also form heterodimers with retinoid X receptor (RXR) alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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