Thermo Fisher Scientific PPARA Monoclonal Antibody (OTI1E11), TrueMAB
Human PPARA 단백질(aa 145-420)을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 ICC/IF에 사용 가능. 1 mg/mL 농도의 액상형 TrueMAB 제품이며, 고순도 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 145–420 of human PPARA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Peroxisome proliferators are non-genotoxic carcinogens that exert their effects through interaction with nuclear hormone receptors termed peroxisome proliferator activated receptors (PPARs). These ligand-dependent intracellular proteins stimulate transcription of specific genes by binding to DNA sequences after activation by appropriate ligands.
PPARs are activated by compounds such as clofibric acid, nafenopin, WY-14,643, and certain fatty acids. They can induce transcription of acyl coenzyme A oxidase and cytochrome P450 (CYP450) A6 through specific response elements.
PPAR, like other nuclear hormone receptors, forms heterodimers with retinoid X receptor (RXR) alpha.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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