Thermo Fisher Scientific PPARA Monoclonal Antibody (OTI3G3), TrueMAB
인간 PPARA 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot, ICC/IF, Flow cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제. PBS, BSA, 글리세롤 기반 안정화 용액. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 145–420 of human PPARA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.56 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Peroxisome proliferators are non-genotoxic carcinogens that exert their effects through interaction with members of the nuclear hormone receptor family termed peroxisome proliferator-activated receptors (PPARs). These nuclear hormone receptors are ligand-dependent intracellular proteins that regulate transcription of specific genes by binding to DNA sequences upon activation by appropriate ligands. PPARs are activated by compounds such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. They can induce transcription of acyl coenzyme A oxidase and cytochrome P450 (CYP450) A6 through specific response elements. PPARs also heterodimerize with retinoid X receptor (RXR) alpha, similar to other nuclear hormone receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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