Thermo Fisher Scientific CD5 Monoclonal Antibody (53-7.3), APC, eBioscience

Thermo Fisher Scientific CD5 Monoclonal Antibody (53-7.3), APC, eBioscience™

Applications

• Flow Cytometry (Flow)

Tested Dilution: 0.25 µg/test
Publications: View 29 publications

Product Specifications

Additional Formats

• Unconjugated
• APC-eFluor 780
• Biotin
• eFluor 450
• FITC
• NovaFluor Blue 610-70S
• NovaFluor Blue 660-120S
• NovaFluor Red 710
• NovaFluor Red 725
• NovaFluor Red 755
• NovaFluor Yellow 610
• NovaFluor Yellow 660
• NovaFluor Yellow 755
• PE
• PE-Cyanine7
• PE-eFluor 610
• PerCP-Cyanine5.5
• Super Bright 436
• Super Bright 600
• Super Bright 702
• Request custom conjugation

Product Specific Information

The 53-7.3 monoclonal antibody reacts with mouse CD5, a 67 kDa protein expressed by most thymocytes, mature T cells, and a subset of B cells. CD5 expression in a small subset of B cells characterizes B-1 cells, a distinct lineage of B cells. CD5 acts as a counter-receptor for CD72 and plays a role in T-B cell interaction.

Applications Reported: Flow cytometric analysis
Applications Tested: Tested on mouse splenocytes; ≤0.25 µg/test (100 µL final volume). Recommended to titrate for optimal performance.
Excitation: 633–647 nm; Emission: 660 nm; Laser: Red Laser
Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD5 is a 67 kDa human T-lymphocyte transmembrane glycoprotein found on mature T cells, thymocytes, and some T-cell leukemias/lymphomas. It also reacts with a subset of activated B cells and may regulate T-cell proliferation. CD5 is expressed on 95% of thymocytes and 72% of peripheral blood lymphocytes. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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