Thermo Fisher Scientific Factor XIII A Monoclonal Antibody (16D1)
Human Factor XIII A 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합합니다. 고순도 Protein A 정제, 2 mg/mL 농도, -20°C 보관 및 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:800 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 16D1 |
| Immunogen | Recombinant protein within Human F13A1 aa 259–463 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848861 |
Product Specific Information
Positive Control: Human placenta tissue lysates, human placenta tissue, MCF-7, MG-63, A549.
Target Information
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of two A subunits and two B subunits. The A subunits have catalytic function, while the B subunits act as carrier molecules. Platelet factor XIII consists only of two A subunits, identical to the plasma form. Upon thrombin activation and calcium presence, plasma factor XIII releases its B subunits and forms the active enzyme, factor XIIIa. This enzyme catalyzes crosslinking between fibrin molecules, stabilizing the clot, and also crosslinks alpha-2-plasmin inhibitor or fibronectin. Factor XIII deficiency can result in bleeding tendency, poor wound healing, and habitual abortion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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