Thermo Fisher Scientific Factor XIII A Monoclonal Antibody (16D3)
Factor XIII A 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, Flow cytometry에 적합합니다. 고순도 Protein A 정제, 2 mg/mL 농도, 안정적인 PBS/glycerol buffer로 장기 보관 가능. 인체 반응성 검증 완료.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:800 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 16D3 |
| Immunogen | Recombinant protein within Human F13A1 aa 259–463 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848860 |
Product Specific Information
Positive Control: Human placenta tissue lysates, human placenta tissue, A549.
Target Information
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits may serve as plasma carrier molecules. Platelet factor XIII consists of only 2 A subunits, identical to those of plasma origin. Upon activation by thrombin and calcium ions, plasma factor XIII dissociates its B subunits and yields the active enzyme factor XIIIa, which acts as a transglutaminase to catalyze crosslinking between fibrin molecules, stabilizing the clot. It also crosslinks alpha-2-plasmin inhibitor or fibronectin to fibrin. Factor XIII deficiency can lead to bleeding tendency, defective wound healing, and habitual abortion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-34954_Factor_XIII_A_P00488-1_House_mouse.svg, MA5-34954_Factor_XIII_A_P00488-1_House_mouse_PDP.jpeg)
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