Thermo Fisher Scientific Langerin Polyclonal Antibody
Langerin(CD207)을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, Flow Cytometry 등 다양한 응용에 사용 가능. Human 및 Mouse 반응성. Protein G 정제, PBS buffer, 1 mg/mL 농도. 연구용으로만 사용.
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Thermo Fisher Scientific Langerin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:20–1:2,000 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 26–44 of mouse Langerin (CD207) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2074208 |
Product Specific Information
This antibody is expected to react with rat samples based on sequence homology.
Target Information
Langerin (CD207) is a type II membrane-associated C-type lectin expressed exclusively by Langerhans cells. It recognizes mannose residues via its carbohydrate recognition domain (CRD) and is localized both on the cell surface and intracellularly, closely associated with Birbeck granules. Transfection of Langerin cDNA into fibroblasts induces formation of membrane structures characteristic of Birbeck granules, acting as a potent inducer of membrane superimposition and zippering leading to BG formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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