Thermo Fisher Scientific Phospho-PLA2G4A (Ser505) Polyclonal Antibody
Phospho-PLA2G4A (Ser505) 폴리클로날 항체로 인간, 마우스, 원숭이, 랫트 반응성. Western Blot과 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 방부제 무첨가, -20°C 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-PLA2G4A (Ser505) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer505 of human cPLA2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 250 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985549 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with the secreted PLA2 (sPLA2) or cytosolic Ca2+ independent PLA2 (iPLA2).
Target Information
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid, which is subsequently metabolized into eicosanoids.
Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways.
The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor.
The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.