Thermo Fisher Scientific H2BK5ac Polyclonal Antibody
H2BK5ac 폴리클로날 항체로 인간, 마우스, 프라이메이트, 랫트 시료에 반응. Western blot, IHC, ICC/IF, IP, ChIP 등 다양한 응용 가능. 합성 아세틸화 펩타이드 기반 면역원 사용. 항원 친화 크로마토그래피로 정제된 액상 형태, -20°C 보관.
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Thermo Fisher Scientific H2BK5ac Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:50 |
| ChIP assay (ChIP) | 1.5 µg/1x10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic acetylated peptide corresponding to residues surrounding Lys5 of human histone H2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988439 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other acetylated histones.
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromatin, limiting DNA accessibility to cellular machineries that require DNA as a template. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(관련 항원 구조 및 이미지 파일: PA5-17779_H2BK5ac 관련 시각 자료)
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