Thermo Fisher Scientific EDG8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

3-6 µg/mL

-

Product Specifications

Species Reactivity

Bat, Human, Non-human primate, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human S1PR5 / EDG8. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EDG8,uniProtId:Q9H228-1,ncbiNodeId:9606,antigenRange:1,antigenLength:398,antigenImageFileName:PA5-34186_EDG8_Q9H228-1_Rabbit.svg,antigenImageFileNamePDP:PA5-34186_EDG8_Q9H228-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2551539

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Elephant, Bat, Pig (100%) Mouse, Rat, Hamster, Dog, Bovine (94%).

Target Information

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.