Thermo Fisher Scientific EDG8 Polyclonal Antibody
Rabbit 폴리클로날 항체로, 인간 및 다양한 종에서 EDG8(S1PR5)을 검출. IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 고순도 항체. 세포 증식 및 신호전달 연구에 적합. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 3–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Human, Non-human primate, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminal extracellular domain of human S1PR5 / EDG8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551539 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Monkey, Marmoset, Elephant, Bat, Pig (100%); Mouse, Rat, Hamster, Dog, Bovine (94%).
Target Information
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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