Thermo Fisher Scientific Human KLF4 Synthetic Peptide
인간 KLF4 단백질의 카복시말단 20개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20897과 함께 차단 실험용으로 사용 가능. 세포 재프로그래밍 및 분화 연구에 활용. PBS 완충액 내 액상 형태로 제공. 연구용 전용 제품.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 20 amino acids near the carboxy terminus of human KLF4.
PEP-1011 can be used as a blocking peptide with polyclonal antibody PA5-20897.
Target Information
Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans.
It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a conserved family of DNA-binding zinc finger transcription factors.
KLF4 plays a key role in reprogramming differentiated cells into pluripotent stem cells as one of the four Yamanaka factors.
It is involved in endothelial cell signaling, adipogenesis, differentiation, embryogenesis, and cell cycle control.
Nuclear localization is associated with its oncogenic function, while cytosolic localization is related to tumor-suppressive effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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