Thermo Fisher Scientific Human LIN28A Synthetic Peptide
휴먼 LIN28A 단백질의 C-말단 15개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-20898의 블로킹 펩타이드로 사용 가능. PBS(pH 7.2)와 0.1% BSA 포함, -20°C 보관. 줄기세포 연구 및 발달 생물학 연구용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human Lin28.
PEP-1012 can be used as a blocking peptide with polyclonal antibody PA5-20898.
Target Information
Lin28 is a transcription factor first identified for its key role in developmental timing in C. elegans. Its function in development suggests its utility in generating stem cells for potential cell replacement therapies in degenerative diseases.
Induced pluripotent stem (iPS) cells can be created by expressing Lin28 along with transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recent studies show that iPS cells can also be generated using expression plasmids for Lin28, Sox2, POU5F1, and c-Myc, eliminating the need for viral introduction and improving safety for regenerative medicine applications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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