Thermo Fisher Scientific Phospho-TrkC (Tyr820) Polyclonal Antibody
Phospho-TrkC (Tyr820)에 특이적인 sheep polyclonal antibody로, 인간·마우스·랫트 시료에 반응합니다. Western blot 및 IHC에 적합하며, 신경계 관련 단백질 NTRK3 연구에 활용됩니다. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C에서 안정적입니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide to phospho Y820 of human TrkC conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: TrkC.
Target Information
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors include SHC, PI-3 kinase, and PLCG1. Different isoforms exhibit distinct signaling properties. The protein is widely expressed, mainly in nervous tissue. Isoform B is more abundant in adult brain compared to fetal brain. TRKC undergoes ligand-mediated auto-phosphorylation and contains two immunoglobulin-like C2-type domains and two leucine-rich (LRR) repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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